Correlation with Hs-CRP,IL-6 and Lp-PLA_2 in Angina Pectoris of Different Blood Stasis Patterns/Syndromes

Objective To explore the correlation with the levels of the high-sensitivity C-reactive protein(Hs-CRP),interleukin-6(IL-6)and lipoprotein-associated phospholipase A2(Lp-PLA2)in the patients with angina pectoris of different blood stasis patterns/syndromes.Methods 150 cases of angina pectoris were differentiated as qi deficiency and blood stasis group(36 cases),turbid phlegm and blood stasis group(45 cases),blood deficiency and blood stasis group(30 cases),qi stagnation and blood stasis group(18 cases),heat toxin and blood stasis group(14 cases)and cold stagnation and blood stasis group(7 cases).The levels of Hs-CRP,IL-6 and Lp-PLA2 were detected separately for statistical analysis.Results Concerning to Lp-PLA2 level,the result in qi deficiency and blood stasis group was higher apparently than that in turbid phlegm and blood stasis group,qi stagnation and blood stasis group,heat toxin and blood stasis group and cold stagnation and blood stasis group(P0.05);the result in blood deficiency and blood stasis group was higher apparently than that in heat toxin and blood stasis group and cold stagnation and blood stasis group(P0.05).Concerning to IL-6 level,the result in turbid phlegm and blood stasis group was higher apparently than the other groups(P0.05).Concerning to Hs-CRP level:the result in turbid phlegm and blood stasis group was higher apparently than that in qi deficiency and blood stasis group,qi stagnation and blood stasis group,heat toxin and blood stasis group and cold stagnation and blood stasis group(P0.05)and the result in blood deficiency and blood stasis group was higher than that in qi deficiency and blood stasis group(P0.05).Conclusion The different blood stasis patterns/syndromes bring a certain changing rule of the inflammatory factors.The levels of Hs-CRP,IL-6 and Lp-PLA2 are probably the objective evidences of the differentiation of blood stasis patterns/syndromes.