Relationship of endometriosis syndrome type and insulin-like growth factor-I

Objective To investigate the relationship of endometriosis syndrome type and insulin-like growth factor-Ⅰ. Methods To select 242 cases as for TCM gynecology gynecology or endometriosis patients and 22 cases of laparoscopic surgery because of infertility or pelvic laparoscopic surgery for benign disease need patients in the control group,using ELISA serum insulin-like growth factor-Ⅰ,immunohistochemical detection of endometrial tissue expression of insulin-like growth factor-Ⅰ. Results The 242 patients with endometriosis in patients with blood stasis type87( 36. 0%),phlegm stasis type 36 cases( 14. 9%),Hanning Blood type 33 cases( 13. 6%),hot Yu blood stasis 24cases( 9. 9%),43 cases of kidney and blood stasis( 17. 8%) and 19 cases of Qi and Blood( 7. 8%). ELISA test results showed no difference in serum QDBS content of IGF-Ⅰ group and the normal control group,the other groups were higher than the normal control group( P 0. 05); blood stasis group,Kidney Blood patients serum IGF-Ⅰ were significantly higher than the other groups( P 0. 05). Immunohistochemistry showed,IGF-Ⅰ in patients with positive expression of tissue syndrome type relative to the control group with statistical significance( P 0. 05,P 0. 01);blood stasis type group IGF-Ⅰ expression rate higher than phlegm stasis group,heat and blood stasis group( P 0. 05); blood stasis group was higher than the other groups( P 0. 05) in the 9-12 score( + + +) entry. Conclusion Endometriosis patients with TCM syndrome type of qi and blood stasis,kidney and blood stasis and blood stasis type haemorrheological nature related to the high expression of IGF-1.