Anesthesia endoscopy injection combined with high dose losec treatment for digestive ulcer hemorrhage

[Objective]To observe the clinical effect of treatment with the anesthesia endoscopic injection combined with large dose losec for peptic ulcer bleeding.[Methods]Total of 90 peptic ulcer patients,were randomly divided into 3groups(n= 30):large doses losec group(group A),with losec 40 mg intravenous injection,3times a day for five days;anesthesia endoscopy injection combine with conventional dose of losec for the treatment group(group B).The patient accepted losec 40 mg intravenous injection before endoscopic examination,sedation with propofol,and 1/10 000 epinephrine injected to stop bleeding,then accepted losec40 mg intravenous injection after endoscopic hemostasis,2times a day for five consecutive day;Anesthesia endoscopy hemostasis combine with large dose of los for the treatment group(group C):losec 40 mg intravenous injection before endoscopic examination,continue to use losec 40 mg intravenous injection after endoscopic hemostasis,3times a day for five consecutive day.The others treatment was similar to group B.[Results]Compared with group A,the hemostatic time in B and C group were shortened,and bleeding rate were declined,operation rate and the length of time were reduced,the differences were statistically significant(P 0.05).Compared with group B,bleeding time in group C was shortened,bleeding rate was declined,operation rate and the length of time were reduced,the differences were statistically significant(P0.05).[Conclusion]Anesthesia endoscopic injection combined with high dose of losec for peptic ulcer hemorrhage is safe and effective,meets the requirements of basic-level hospitals,also meet the demand of patients comfortable personalized medical,is worthy of popularizing in basic-level hospitals.