Application of remifentanil combined with sevoflurane anesthesia in laparoscopic operation

Objective To investigate the effects of remifentanil combined with sevoflurane on hemodynamics in patients undergoing laparoscopic operation.Methods Thirty-five cases (ASA Ⅰ or Ⅱ,male 6,female 29) undergoing laparoscopic cholecystectomy or gynecology surgery were induced with remifentanil 1.0 μg/kg,midazolame 2-3 mg,propofol 1-2 mg/kg,vecuronium 8 mg,and maintained with remifentanil 0.2 μg·kg-1·min-1,propofol 2 mg·kg-1·min-1 and 1%-2% sevoflurane inhalation.The hemodynamics were recorded before and during anesthesia.Results There was a significant decrease in BP,HR after remifentanil injection,even more after propofol.BP and HR were increased markedly after intubation and decreased significantly during skin incision.CO,SV and CI were decreased significantly after pneumoperitoneum and returned or even higher than the basic levels after deflation.Conclusion The short action and rapid recovery characteristics of remifentanil combined with srvoflurane anesthesia is suitable for laparoscopic operation.