Application of remifentanil combined with sevoflurane anesthesia to laparoscopic cholecystectomy

【Objective】To investigate the effects of propofol/remifentanil,sevoflurane/remifentanil anesthesia in laparoscopic cholecystectomy.【Methods】Forty ASA I or II patients undergoing laparoscopic cholecystectomy were randomly divided into two groups:propofol group(n =20,group P) and sevoflurane group(n =20,group S),these cases were induced with midazolame 0.1 mg/kg,remifentanil 1 μg/(kg·min),propofol 2.0 mg/kg,rocuronium 0.6 mg/ kg.After rapid induction all patients were intubated with a tube.Anesthesia was maintained with continuous infusion of 3%-4% end-tidal concentration of sevoflurane and remifentanil 0.5 μg/(kg·min) in group S,propofol 60-100μg/(kg·min) and remifentanil 0.5 μg/(kg·min) in group P.The recovery time,BP and HR in both groups were observed.【Results】 There was no statistical difference in recovery time between the groups.The changes of SBP,DBP and HR were more obvious in group P than those in group S(P 0.05).【Conclusion】The short action and rapid recovery characteristics of remifentanil combined with sevoflurane anesthesia is suitable for laparoscopic cholecystectomy.