Optimization of Ethanol Extraction Process of Compound Gouteng Tablet

Objective:To optimize ethanol extraction technology of compound Gouteng tablet.Method:Ethanol extraction technology were optimized by orthogonal test with yield of extract and rhynchophylline as indexes,with the amount of ethanol,extraction time and soaking time as factors,the content of rhynchophylline was determined by HPLC.The concentraction of ethanol was investigated by single factor test.Result:Optimum ethanol extraction process was as follows:soaked in 80% ethanol for 0.5 h,reflux extracted 2 times with 6,4 times the amount of 80% ethanol by 2.0,1.5 h,respectively.Conclusion:Optimum extraction process was stable,feasible,and suitable for industrial production.