Clinical study of plasma brain natriuretic peptide in the diagnosis of heart failure

Objective To investigate the value of plasma brain natriuretic peptide level in diagnosis of heart failure and its significance in assessing cardiac function.Methods One hundred and thirteen patients with heart failure as heart failure group,and 100 healthy persons as control group were selected to determine the plasma BNP level by the rapid fluorescent dry quantitative analyzer and immunofluorescence method.Then the heart failure patients was graded according to the New York Heart Association classification scheme for classification of cardiac function.Results The plasma BNP concentration in HF group was higher than that of the control group( P 0.05).The plasma BNP concentration increased in patients with HF heart function grade,and the difference between the groups was statistically significant.Conclusion Plasma BNP is an objective index to reflect the cardiac function,having an important significance in diagnosis and cardiac function evaluation of heart failure.