Comparative study on clinical therapeutic effect of insulin aspart and biosynthetic human insulin in the treatment of newly diagnosed type 2 diabetes
Zhongying Chen
Abstract
Zhongying Chen
Abstract
Objective To compare the clinical efficacy between insulin aspart and biosynthetic human insulin in the treatment of newly diagnosed type 2 diabetes.Methods Ninety-six newly diagnosed type 2 diabetic patients were randomly divided into insulin aspart group(treatment group,n=48) and biosynthetic human insulin group(control group,n=48).The patients received subcutaneous injection of insulin aspart or biosynthetic human insulin before daily meals,and they were treated with insulin glargine at the bedtime.The blood sugar levels,incidence of hypoglycemic episodes and the dosage of insulin were compared between the two groups.Results After administration of the drugs,the blood sugar levels were significantly reduced,and the blood sugar levels was lower in insulin aspart group than in the control group.The incidence of hypoglycemia in the treatment group was lower than in the control group,and the difference was statistically significant.The dosage of insulin showed no significant difference in the two groups.Conclusion Insulin aspart was better in the control of blood sugar levels and more effective in the treatment of patients with type 2 diabetes.
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Objective To compare the clinical efficacy between insulin aspart and biosynthetic human insulin in the treatment of newly diagnosed type 2 diabetes.Methods Ninety-six newly diagnosed type 2 diabetic patients were randomly divided into insulin aspart group(treatment group,n=48) and biosynthetic human insulin group(control group,n=48).The patients received subcutaneous injection of insulin aspart or biosynthetic human insulin before daily meals,and they were treated with insulin glargine at the bedtime.The blood sugar levels,incidence of hypoglycemic episodes and the dosage of insulin were compared between the two groups.Results After administration of the drugs,the blood sugar levels were significantly reduced,and the blood sugar levels was lower in insulin aspart group than in the control group.The incidence of hypoglycemia in the treatment group was lower than in the control group,and the difference was statistically significant.The dosage of insulin showed no significant difference in the two groups.Conclusion Insulin aspart was better in the control of blood sugar levels and more effective in the treatment of patients with type 2 diabetes.
Key concepts: Medicine, Insulin aspart, Insulin, Hypoglycemia, Internal medicine, Blood sugar, Diabetes mellitus, Type 2 diabetes