2012•Journal of Clinical Medicine in PracticeRequires access

Comparative study on clinical therapeutic effect of insulin aspart and biosynthetic human insulin in the treatment of newly diagnosed type 2 diabetes

Zhongying Chen

Open publisher page 0 citations

Abstract

Objective To compare the clinical efficacy between insulin aspart and biosynthetic human insulin in the treatment of newly diagnosed type 2 diabetes.Methods Ninety-six newly diagnosed type 2 diabetic patients were randomly divided into insulin aspart group(treatment group,n=48) and biosynthetic human insulin group(control group,n=48).The patients received subcutaneous injection of insulin aspart or biosynthetic human insulin before daily meals,and they were treated with insulin glargine at the bedtime.The blood sugar levels,incidence of hypoglycemic episodes and the dosage of insulin were compared between the two groups.Results After administration of the drugs,the blood sugar levels were significantly reduced,and the blood sugar levels was lower in insulin aspart group than in the control group.The incidence of hypoglycemia in the treatment group was lower than in the control group,and the difference was statistically significant.The dosage of insulin showed no significant difference in the two groups.Conclusion Insulin aspart was better in the control of blood sugar levels and more effective in the treatment of patients with type 2 diabetes.

About this research paper

What this paper is about

Objective To compare the clinical efficacy between insulin aspart and biosynthetic human insulin in the treatment of newly diagnosed type 2 diabetes.Methods Ninety-six newly diagnosed type 2 diabetic patients were randomly divided into insulin aspart group(treatment group,n=48) and biosynthetic human insulin group(control group,n=48).The patients received subcutaneous injection of insulin aspart or biosynthetic human insulin before daily meals,and they were treated with insulin glargine at the bedtime.The blood sugar levels,incidence of hypoglycemic episodes and the dosage of insulin were compared between the two groups.Results After administration of the drugs,the blood sugar levels were significantly reduced,and the blood sugar levels was lower in insulin aspart group than in the control group.The incidence of hypoglycemia in the treatment group was lower than in the control group,and the difference was statistically significant.The dosage of insulin showed no significant difference in the two groups.Conclusion Insulin aspart was better in the control of blood sugar levels and more effective in the treatment of patients with type 2 diabetes.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To compare the clinical efficacy between insulin aspart and biosynthetic human insulin in the treatment of newly diagnosed type 2 diabetes.Methods Ninety-six newly diagnosed type 2 diabetic patients were randomly divided into insulin aspart group(treatment group,n=48) and biosynthetic human insulin group(control group,n=48).The patients received subcutaneous injection of insulin aspart or biosynthetic human insulin before daily meals,and they were treated with insulin glargine at the bedtime.The blood sugar levels,incidence of hypoglycemic episodes and the dosage of insulin were compared between the two groups.Results After administration of the drugs,the blood sugar levels were significantly reduced,and the blood sugar levels was lower in insulin aspart group than in the control group.The incidence of hypoglycemia in the treatment group was lower than in the control group,and the difference was statistically significant.The dosage of insulin showed no significant difference in the two groups.Conclusion Insulin aspart was better in the control of blood sugar levels and more effective in the treatment of patients with type 2 diabetes.

Key concepts: Medicine, Insulin aspart, Insulin, Hypoglycemia, Internal medicine, Blood sugar, Diabetes mellitus, Type 2 diabetes

Related papers

Back to paper searchBrowse research topicsOriginal source
Comparative study on clinical therapeutic effect of insulin aspart and biosynthetic human insulin in the treatment of newly diagnosed type 2 diabetes — Research Paper | ScholarLens