2011•The Chinese Journal of Clinical PharmacologyRequires access

Clinical observation of intensive insulin aspart in the treatment of newly diagnosed type 2 diabetes

Lianye Liu

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Abstract

Objective To observe the clinical effect and safety of insulin aspart and human insulin for type 2 diabetes.Methods The newly diagnosed type 2 diabetic patients were divided into two groups randomly and treated with intensive insulin therapy four times per day.Half of the patients were treated with thrice preprandial injection of insulin aspart.Correspondingly,others were treated with human insulin.All the patients were treated with isophane protamine biosynthetic human insulin injection at bedtime.The blood glucose lever,occurrence of hypoglycemia,dosage of insulin,and therapeutic time were investigated.Results The incidence of hypoglycemia in the patients with insulin aspart therapy was lower remarkably than the control group.The dosage of insulin and therapeutic time were similar in two groups.Conclusion Insulin aspart is more effective and safe for type 2 diabetic patients.

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What this paper is about

Objective To observe the clinical effect and safety of insulin aspart and human insulin for type 2 diabetes.Methods The newly diagnosed type 2 diabetic patients were divided into two groups randomly and treated with intensive insulin therapy four times per day.Half of the patients were treated with thrice preprandial injection of insulin aspart.Correspondingly,others were treated with human insulin.All the patients were treated with isophane protamine biosynthetic human insulin injection at bedtime.The blood glucose lever,occurrence of hypoglycemia,dosage of insulin,and therapeutic time were investigated.Results The incidence of hypoglycemia in the patients with insulin aspart therapy was lower remarkably than the control group.The dosage of insulin and therapeutic time were similar in two groups.Conclusion Insulin aspart is more effective and safe for type 2 diabetic patients.

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Available abstract

Objective To observe the clinical effect and safety of insulin aspart and human insulin for type 2 diabetes.Methods The newly diagnosed type 2 diabetic patients were divided into two groups randomly and treated with intensive insulin therapy four times per day.Half of the patients were treated with thrice preprandial injection of insulin aspart.Correspondingly,others were treated with human insulin.All the patients were treated with isophane protamine biosynthetic human insulin injection at bedtime.The blood glucose lever,occurrence of hypoglycemia,dosage of insulin,and therapeutic time were investigated.Results The incidence of hypoglycemia in the patients with insulin aspart therapy was lower remarkably than the control group.The dosage of insulin and therapeutic time were similar in two groups.Conclusion Insulin aspart is more effective and safe for type 2 diabetic patients.

Key concepts: Insulin aspart, Medicine, Hypoglycemia, Insulin, Bedtime, Internal medicine, Type 2 diabetes, Diabetes mellitus

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