Application research of rapidly acting insulin aspart and human insulin in insulin pump therapy

Objective: To compare the effectiveness,security and application characteristics of rapidly acting insulin analogues(aspart) and human insulin(Humulin R) used in insulin pump in treating type 2 diabetes.Methods: Collected 60 type 2 diabetic patients and randomly divided into 2 groups with 30 patients in each group.Group A was treated with insulin aspart and group B with Humulin R.Results: After treatment,the fasting blood glucose and 2 hour post-meal blood sugar significantly decreased in the two groups(P0.05).Compared with the group B,the treatment of insulin aspart shortened the therapeutic time(4.20±1.86d vs 6.28±1.89d),reduced the amount of insulin dose in blood glucose control and the daily insulin dosage(P0.05).The hypoglycemia incidence in group A was significantly lower than that in group B.Conclusion: Insulin aspart is a kind of effective anti-diabetic drug in CSII therapy.