Comparison of the Application value of Cardiac troponin I(cTnI),cardiac troponin T(cTnT),and creatine kinase MB(CK-MB) for the diagnosis of acute myocardial infarction(AMI)

Objective To observe the application value of cardiactroponinI(cTnI),cardiac troponin T(cTnT) and creatine kinase MB(CK-MB) for the early diagnosis of acute myocardial infarction(AMI).Methods to determin the plasma level of cTnI、cTnT and CK-MB in patients(23 with acute myocardial infarction,18 patients with unstable angina and 23 patients with other diseases).Comparison between AMI and UA was performed and all the indexes were analysed contrastively.Results The sensitivity of cTnI and cTnT in diagnosing AMI are higher than that of CK-MB,and their positive rates were 82.6%,95.7% and 43.5% respectively.while in UA,their rates are 22.2%,38.9%,and 11.1%,obviously lower than that of AMI.Conclusion cTnI and cTnT,as specific markers of cardiac damage,are more sensitive and specific in the early diagnosis of AMI,more reliable than CK-MB.While in the early period of AMI,detecting cTnI is a more convenient,swift and accurate measurement method,and has significant clinical value.