Clinical comparison of the sensitivity and specificity of cardiac tro ponin I and cardiac troponin T and creatine kinase MB for the early diagnosis of acute myocardial infarction

To observe the application value of cardiac troponin I(cTnI),cardiac troponin T (cTnT) and creatine kinase MB (CK-MB) for the early diagnosis of acute myocardial infarction (AMI).Methods The same serum sample was measured to detect the indexes of cTnI,cTnT and CK-MB levels in 60 patients with AMI and 40 patients with UA.Comparison between AMI and UA was performed and all the indexes were analysed contrastively.Results The sensitivity of cTnI and cTnT was higher than that of CK-MB,and their positive rates were 63.3%,46.7% and 18.3% respectively (P＜0.01) .There was no significant difference between cTnI and cTnI (P＞0 .05) and the specificity of the three indexes were almost the same without signi ficant difference.Conclusion cTnI and cTnT,as specific markers of cardiac damage,are more sensitive and specific in the early diagnosis of AMI. As a convenient,swift and accurate measurement method,cTnI has significant clinical value.