2013China Medicine and PharmacyRequires access

Urogenital Tract Mycoplasma Infection and Drug Resistance Analysis

Shaofeng Zhu

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Abstract

Objective To better guide clinical rational drug use and promote curative effect through understanding the urogenital tract infection situation and antibiotic resistance analysis. Methods The mycoplasma culture and identification drug susceptibility kit produced by Zhuhai Langfeng Biological Limited Company was used to cultivate Ureaplasmalyticum (Uu) and Mycoplasma hominis (Mh) and test drug susceptibility. Results The positive detection rate of was 57%, of which the Uu detection rate was the highest, accounting for 69.5%, the Mh detection rate was relatively low, accounting for 9.5%, and the combined Uu and Mh infection detection rate was 21%. The drug susceptibility test showed that had the highest drug resistance rate toward ciprofloxacin (CPF), accounting for 81%, followed by levofloxacin (CRA), accounting for 63.1%. Mycoplasma had the lowest drug resistance rate toward minocycline (MIV), accounting for 0.35%. The drug resistance rates toward gatifloxacin (GAT), thiamphenicol (THI), roxithromycin (ROX), erythromycin (ERY), azithromycin (AZI), cycloaliphatic neomycin (ECC), clarithromycin (CLA) , doxycycline (DOX) and josamycin (JOS) were 57.9%, 43.2% 37.9% 35.8% 31.6%, 22.1%, 20%, 4.2% and 1.8% respectively. Conclusion The culture of urogenital tract secretion and the drug susceptibility test play an important role in guiding the clinical diagnosis and treatment. Clinicians should use antibiotics rationally based on the drug susceptibility results.

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Objective To better guide clinical rational drug use and promote curative effect through understanding the urogenital tract infection situation and antibiotic resistance analysis. Methods The mycoplasma culture and identification drug susceptibility kit produced by Zhuhai Langfeng Biological Limited Company was used to cultivate Ureaplasmalyticum (Uu) and Mycoplasma hominis (Mh) and test drug susceptibility. Results The positive detection rate of was 57%, of which the Uu detection rate was the highest, accounting for 69.5%, the Mh detection rate was relatively low, accounting for 9.5%, and the combined Uu and Mh infection detection rate was 21%. The drug susceptibility test showed that had the highest drug resistance rate toward ciprofloxacin (CPF), accounting for 81%, followed by levofloxacin (CRA), accounting for 63.1%. Mycoplasma had the lowest drug resistance rate toward minocycline (MIV), accounting for 0.35%. The drug resistance rates toward gatifloxacin (GAT), thiamphenicol (THI), roxithromycin (ROX), erythromycin (ERY), azithromycin (AZI), cycloaliphatic neomycin (ECC), clarithromycin (CLA) , doxycycline (DOX) and josamycin (JOS) were 57.9%, 43.2% 37.9% 35.8% 31.6%, 22.1%, 20%, 4.2% and 1.8% respectively. Conclusion The culture of urogenital tract secretion and the drug susceptibility test play an important role in guiding the clinical diagnosis and treatment. Clinicians should use antibiotics rationally based on the drug susceptibility results.

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Available abstract

Objective To better guide clinical rational drug use and promote curative effect through understanding the urogenital tract infection situation and antibiotic resistance analysis. Methods The mycoplasma culture and identification drug susceptibility kit produced by Zhuhai Langfeng Biological Limited Company was used to cultivate Ureaplasmalyticum (Uu) and Mycoplasma hominis (Mh) and test drug susceptibility. Results The positive detection rate of was 57%, of which the Uu detection rate was the highest, accounting for 69.5%, the Mh detection rate was relatively low, accounting for 9.5%, and the combined Uu and Mh infection detection rate was 21%. The drug susceptibility test showed that had the highest drug resistance rate toward ciprofloxacin (CPF), accounting for 81%, followed by levofloxacin (CRA), accounting for 63.1%. Mycoplasma had the lowest drug resistance rate toward minocycline (MIV), accounting for 0.35%. The drug resistance rates toward gatifloxacin (GAT), thiamphenicol (THI), roxithromycin (ROX), erythromycin (ERY), azithromycin (AZI), cycloaliphatic neomycin (ECC), clarithromycin (CLA) , doxycycline (DOX) and josamycin (JOS) were 57.9%, 43.2% 37.9% 35.8% 31.6%, 22.1%, 20%, 4.2% and 1.8% respectively. Conclusion The culture of urogenital tract secretion and the drug susceptibility test play an important role in guiding the clinical diagnosis and treatment. Clinicians should use antibiotics rationally based on the drug susceptibility results.

Key concepts: Medicine, Gatifloxacin, Roxithromycin, Josamycin, Drug resistance, Levofloxacin, Mycoplasma, Antibiotics

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