Analysis for 340 Cases of Pseudomonas Aeruginosa Infection and Drug Resistance

Objective To investigate Pseudomonas aeruginosa infection distribution and drug resistance of different types of antibacterial agents in our hospital from January to December on 2009,to guide the clinical rational use of medicines.Methods 340 cases of Pseudomonas aeruginosa infection in our hospital were collected,the distribution of clinical infection,bacterial resistance and retrospectively clinical medication were analyzed,respectively.Results The most Pseudomonas aeruginosa were isolated from sputum samples,with the positive rate as 80.3%;the highest sensitive agent to Pseudomonas aeruginosa was polymyxin(account for 97.1%),followed by amikacin(91.8%),obramycin(83.2%);the highest resistance was SMZ-TMP(account for 97.4%),followed by klinomycin(92.6%),mezlocillin(70.9%).The metalloenzyme masculine strain was only sensitive to polymyxin B,while resistant to other antibiotics.Conclusion Pseudomonas aeruginosa infection in hospital is in a tough situation.The drug sensitivity results suggest that doctors should choose antibiotics reasonable,in order to reduce the emergence of drug-resistant strains.