ANALYSIS OF INFECTION DISTRIBUTION AND DRUG RESISTANCE OF PSEUDOMONAS AERUGINOSA

Objective:To investigate the clinical distribution and drug resistance of Pseudomonas aeruginosa and to offer basis for the clinical therapeutics.Methods:Analyze the infection distribution and drug resistance of 416 samples of Pseudomonas aeruginosa that were isolated from various kinds of specimens from inpatients.The drug sensitivity test was done by means of dilution,and the results were assessed with Clinical and Laboratory Standards Institute.Results:Pseudomonas aeruginosa samples were mainly distributed in intensive care unit(ICU)ward and Respiration department.The highest positive rate of Pseudomonas aeruginosa was in sputum(83.9%).The resistance rates to Imipenem(15.2%)were the lowest.and to Piperacillin/Tazobactam(22.3%)came to be next.Pseudomonas aeruginosa were high resistant to other 11 tested antibiotics.Conclusions Pseudomonas aeruginosa is a common pathogen of respiratory tract infection,which has a high resistance rate to the current clinical antibacterial agents.Consequently,clinical doctors should consider the infection results from Pseudomonas aeruginosa to increase the positive effect and reduce drug resistance rate.