Efficacy and safety of repaglinide in type 2 diabetic patients

Objective:To evaluate the efficacy and safety of Repaglinde in type 2 diabeticpatients Methods:64 type 2 diabetic patients were assigned to Repaglinide or Glurenorm treatment group in 31:33 ratio Results:After 4 weeks of treatment,in the Repaglinide group the mean reduction of FBG and 2hPG was 2 06mmol/L and 7 03mmol/L respectively (P0 05) in the Glurenorm group,the mean reduction of FBG and 2hPG was 1.94mmol/L and 7.05mmol/L respectively (P0.05) The difference in reduction of FBG and 2hPG between the 2 groups was not statistically significant Furthemore,Frequency of hypoglycemia in the Repqglinide group was 3 2%,while that of Glurenorm group was 12 1% Conclusion:In comparision to Glurenorm,Repaglinide provides equal efficacy in metabolic control and afforded a significantly superior safey profile so that patients treated with it had higher treatment compliance