The early diagnostic value of perfusion MSCT in acute cerebral ischemia

Objective:To investigate the early diagnostic value of multi-slice computed tomographic perfusion imaging (MSCTPI) in acute cerebral ischemia.Methods:Conventional computed tomography (CT) and CTPI were performed in turn within 1～12 hours of symptom onset in 21 patients with acute cerebral ischemi diagnosed by clinic.All patients were counterchecked by regular CT in 3～7days.Results:In 21 cases,3 cases diagnosed as cerebral infarction obtained regular CT positive results. In 18 having regular CT negative results,16 had cerebral infarction,and the other 2 had transient ischemic attack(TIA). 17 cases were confirmed by CTPI as having ischemic lesions, whose regional cerebral blood flow(rCBF),time to peak(TP),mean transit time(MTT) in 17 cases with CTPI positive were found obviously changed.The side of ischemic lesion as compared with the opposite,and the core of ischemic lesion as compared with peripheral zone were found changed significantly (P0.05).Conclusion:The development of MSCT accelerate the application of CTPI in acute cerebral ischemia,which can be used to determine the position,range and area of the ischemic lesion and penumbra by analysis on blood perfusion state.It should be meaningful for evaluating prognosis and giving effectual treatment to the patients with acute cerebral ischemia.CTPI has little sensitivity in confirming the ischemic lesion out of the ROl or with small volume.