2015Clinical MedicineOpen access

Efficacy study of amiodarone combined with small dose of metoprolol on treating AMI and ventricular arrhythmia

Sheng Yan-hu

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Abstract

Objective To observe the clinical efficacy of amiodarone combined with small dose of metoprolol on acute myocardial infarction( AMI) and ventricular arrhythmia. Methods Seventy-six patients with AMI and ventricular arrhythmias were selected as research objects and divided into two groups,the patients in control group were given amiodarone treatment,and the patients in the observation group were given small dose of metoprolol in addition. The clinical effects of two groups of patients were observed and HR,LVEF,LVEDV value after treatment was recorded. Results The effective rate of treatment group( 84. 21%) was higher than that of the control group( 63. 16%). The effective rate of treatment group for ventricular arrhythmia was 92. 11% and was 63. 86% in control group,there was significant difference( P 0. 05). The observation group after treatment,HR,LVEDV were( 67. 26 ± 21. 08) beat / min and( 128. 67 ± 22. 58) ml,which was lower than that of control group,LVEF [( 42. 36 ± 5. 54) ml] was higher than that of control group, there were significant differences( P 0. 05).Conclusion On the basis of amiodarone in the treatment of AMI and ventricular arrhythmia,small dose of metoprolol can improve the clinical efficacy and improve heart function of patients.

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What this paper is about

Objective To observe the clinical efficacy of amiodarone combined with small dose of metoprolol on acute myocardial infarction( AMI) and ventricular arrhythmia. Methods Seventy-six patients with AMI and ventricular arrhythmias were selected as research objects and divided into two groups,the patients in control group were given amiodarone treatment,and the patients in the observation group were given small dose of metoprolol in addition. The clinical effects of two groups of patients were observed and HR,LVEF,LVEDV value after treatment was recorded. Results The effective rate of treatment group( 84. 21%) was higher than that of the control group( 63. 16%). The effective rate of treatment group for ventricular arrhythmia was 92. 11% and was 63. 86% in control group,there was significant difference( P 0. 05). The observation group after treatment,HR,LVEDV were( 67. 26 ± 21. 08) beat / min and( 128. 67 ± 22. 58) ml,which was lower than that of control group,LVEF [( 42. 36 ± 5. 54) ml] was higher than that of control group, there were significant differences( P 0. 05).Conclusion On the basis of amiodarone in the treatment of AMI and ventricular arrhythmia,small dose of metoprolol can improve the clinical efficacy and improve heart function of patients.

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Available abstract

Objective To observe the clinical efficacy of amiodarone combined with small dose of metoprolol on acute myocardial infarction( AMI) and ventricular arrhythmia. Methods Seventy-six patients with AMI and ventricular arrhythmias were selected as research objects and divided into two groups,the patients in control group were given amiodarone treatment,and the patients in the observation group were given small dose of metoprolol in addition. The clinical effects of two groups of patients were observed and HR,LVEF,LVEDV value after treatment was recorded. Results The effective rate of treatment group( 84. 21%) was higher than that of the control group( 63. 16%). The effective rate of treatment group for ventricular arrhythmia was 92. 11% and was 63. 86% in control group,there was significant difference( P 0. 05). The observation group after treatment,HR,LVEDV were( 67. 26 ± 21. 08) beat / min and( 128. 67 ± 22. 58) ml,which was lower than that of control group,LVEF [( 42. 36 ± 5. 54) ml] was higher than that of control group, there were significant differences( P 0. 05).Conclusion On the basis of amiodarone in the treatment of AMI and ventricular arrhythmia,small dose of metoprolol can improve the clinical efficacy and improve heart function of patients.

Key concepts: Metoprolol, Medicine, Amiodarone, Cardiology, Ejection fraction, Internal medicine, Myocardial infarction, Clinical efficacy

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