Efficacy analysis of Metoprolol combined amiodarone in chronic heart failure and ventricular arrhythmias

Objective To evaluate the clinical efficacy of combined metoprolol and amiodarone treatment of chronic heart failure and ventricular arrhythmias.Methods Our hospital from February 2008 to May 2011 were treated with chronic heart failure and ventricular arrhythmias in 50 patients,on a voluntary basis to 50 patients divided into combined treatment group of 30 patients and a control group of 20 patients in the control group with amiodarone,combination therapy group received treatment based on the combination of metoprolol treatment.Results The two groups of patients treated control group improved heart function after total effective rate was 83.3%,the combined treatment group was 65.0%.The difference was significant(P0.05).Control group,improvement of ventricular arrhythmias total effective rate was 90.0%,the combined treatment group was 75.0%.The difference was significant(P0.05).The detection of indicators before and after treatment compared combination therapy group was significantly better than that of the control group.Conclusions The combined amiodarone and metoprolol treatment of chronic heart failure with ventricular arrhythmias has good clinical efficacy in reducing ventricular arrhythmias and improve cardiac function is superior to amiodarone alone group,and no incidence of adverse reactions increased significantly.