MSCT assessment of coronary artery soft plaque stenosis and left ventricular systolic function

Objective To observe the clinical application value of coronary artery soft plaque stenosis,and left ventricular function with MSCT in patients with suspected coronary artery disease.Methods Totally 232 patients were retrospectively analyzed with MSCT coronary angiography,including 46 of pure soft plaque and 186 of coronary artery without stenosis.All patients were divided into 4 groups according to coronary vessel diameter(normal,mild stenosis,moderate stenosis,severe stenosis),and left ventricular end-diastolic volume(EDV),left ventricular end systolic volume(ESV),left ventricular stroke volume(SV),left ventricular ejection fraction(EF) were calculated.Results EF values of the mild,moderate stenosis and the normal groups were not statistically different,while statistically significant differences were found among other groups(P0.01).ESV in mild stenosis,moderate stenosis and normal groups were not significantly different,but the difference among the other groups were statistically significant(P0.01).EDV,SV,heart rate were not statistically significant among all 4 groups(P0.05).Conclusion Coronary CT angiography can assess coronary artery stenosis.When coronary artery diameter stenosis was larger than 50%,left ventricular systolic function decreased in varying degrees.When the coronary artery diameter stenosis was larger than 75%,left ventricular systolic function reduced significantly.MSCT can accurately and reliably evaluate the coronary artery stenosis and left ventricular systolic function.