Correlation between the severity of coronary artery stenosis,left ventricle anatomy and systolic function evaluated with multi-slice spiral CT

Objective To observe the correlation between severity of coronary artery stenosis,left ventricle anatomy and systolic function evaluated with MSCT.Methods Two hundred patients with suspected coronary heart disease(CHD)underwent MSCT coronary artery angiography(MSCTCA).According to 17-segment modified American Heart Association classification,the stenosis of each branch segment was assessed with Gensini's score(GS).The raw data of MSCTCA,parameters of left ventricular structure and function,as well as the relationship among them were evaluated only in a one-stop manner.Results GS was grouped according to quartile values.There were significant differences in left ventricular end diastolic dimension(LVDD),left atrium end-diastolic dimension(LADD),left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV),myocardial mass(MM),left ventricular ejection fraction(LVEF)and fraction shortening(FS)(P0.05),but differences in stroke volume(SV),cardiac output(CO)were no significant(P0.05).GS was positively correlated with LVDD,LADD,LVEDV,LVESV and MM,but negatively correlated with LVEF and FS(P0.05),and was no significantly correlated with SV and CO(P0.05).Conclusion The more the stenosis coronary artery,the worse the left ventricle systolic function.Coronary artery stenosis is an important cause of left ventricular systolic dysfunction and cardiac remodeling.