Analysis of 223 Case of Ovarian Neoplasms in Young Women Aged Under 30 Years Old

Objective:To study the characteristic on clinical features, histological type, stage, treatment and outcome of ovarian neoplasm in young women under 30 years old.Methods:A total of 223 cases of ovarian neoplasm in young women less than 30 years old between Oct 1992 and Oct 2007 were analyzed retrospectively.Results:71.30%(168 of all 223 cases) had obvious clinical symptoms.192 cases(86.10%) were benign tumors and 31 cases(13.90%) were malignant tumors.91 cases were ovarian germ cell tumor, 72 cases were epithelial ovarian tumor, 9 cases were ovarian gonadal sex cord stromal tumor, and 51 cases were tumor-like disease.The incidence of ovariectomy in the group of ovarian torsion was higher than that of the group without torsion.In the malignant group, 28 cases were stageⅠ,1 cases was stage Ⅱ, and 2 cases were stage Ⅲ.Of all the cases, 22 patients were treated with conservative surgery, 11 patients of LMP without chemotherapy, and 19 patients of malignant tumors without chemotherapy.During the follow-up period ranged from 10 to 181 months, 27 patients were alive and free of tumor and 4 patients died.21 patients had normal menstruation.Nine patients desired to childbearing had 7 times of pregnancy and 4 times of successful delivery.5-year survival rate was 80.21% respectively.Stage was the most important factor on survival.Conclusion:Benign tumor is the most common ovarian tumor in young women under 30 years old is and germ cell tumor is the most common subtype.Young patients with malignant tumors appear to have favorable stage.Conservative surgery which saves the patient's fertility was preferred treatment strategy in young patients with malignant tumors.Standardized chemotherapy has no effect on fertility function.More attention should be paid on the symptoms and check-up regularly are highly recommended for these patients .