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2009•Practical Clinical MedicineRequires access

Clinical Study of 5-aminolevulinic Acid-Photodynamic Therapy for Condyloma Acuminatum

TU Han-deng

Open publisher page 1 citations

Abstract

Objective To explore the efficacy and safety of 5-aminolevulinic acid photodynamic therapy(ALA-PDT) using thermosensitive gel as photosensitizer vector in the treatment of condyloma acuminatum.Methods 50 patients with condyloma acuminatum were treated by ALA PDT(observer group),and other 54 patients treated by CO2 laser as control group.Results 32 cases of observer group fully recovered after 4 times of PDT,and 6 cases recured,the recurrence rate was 12.0%.34 cases had recurrence in CO2 laser treatment group,the recurrence rate was 62.9%.There was statistically significant difference between two groups(P0.05).Conclusion ALA-PDT using thermosensitive gel as photosensitizer vector can reduce the recurrence rate of condyloma acuminatum and has a better safety.

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What this paper is about

Objective To explore the efficacy and safety of 5-aminolevulinic acid photodynamic therapy(ALA-PDT) using thermosensitive gel as photosensitizer vector in the treatment of condyloma acuminatum.Methods 50 patients with condyloma acuminatum were treated by ALA PDT(observer group),and other 54 patients treated by CO2 laser as control group.Results 32 cases of observer group fully recovered after 4 times of PDT,and 6 cases recured,the recurrence rate was 12.0%.34 cases had recurrence in CO2 laser treatment group,the recurrence rate was 62.9%.There was statistically significant difference between two groups(P0.05).Conclusion ALA-PDT using thermosensitive gel as photosensitizer vector can reduce the recurrence rate of condyloma acuminatum and has a better safety.

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Available abstract

Objective To explore the efficacy and safety of 5-aminolevulinic acid photodynamic therapy(ALA-PDT) using thermosensitive gel as photosensitizer vector in the treatment of condyloma acuminatum.Methods 50 patients with condyloma acuminatum were treated by ALA PDT(observer group),and other 54 patients treated by CO2 laser as control group.Results 32 cases of observer group fully recovered after 4 times of PDT,and 6 cases recured,the recurrence rate was 12.0%.34 cases had recurrence in CO2 laser treatment group,the recurrence rate was 62.9%.There was statistically significant difference between two groups(P0.05).Conclusion ALA-PDT using thermosensitive gel as photosensitizer vector can reduce the recurrence rate of condyloma acuminatum and has a better safety.

Key concepts: Photodynamic therapy, Medicine, Condyloma Acuminatum, Photosensitizer, Clinical efficacy, Significant difference, Dermatology, Surgery

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