2006Xinxiang yixueyuan xuebaoRequires access

Chemical constituents of Isodon macrophylla

Yongxue Wang

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Abstract

Objective To explore the chemical constituents of Isodon macrophyllus.Methods Compounds were separated and purified by silica gel column chromatography and their structures were elucidated on the basis of spectral data and chemical evidences. Results Six compounds were obtained from EtOAc extract of leaves of Isodon macrophyllus and identified as Epinodosin (1),Isodonoiol (2),Lasiodonin (3), Oridonin (4),Adenolin E (5),Lasiodin (6).Conclusion All of them are known.Compound 5 is isolated from this plant for the first time.

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Objective To explore the chemical constituents of Isodon macrophyllus.Methods Compounds were separated and purified by silica gel column chromatography and their structures were elucidated on the basis of spectral data and chemical evidences. Results Six compounds were obtained from EtOAc extract of leaves of Isodon macrophyllus and identified as Epinodosin (1),Isodonoiol (2),Lasiodonin (3), Oridonin (4),Adenolin E (5),Lasiodin (6).Conclusion All of them are known.Compound 5 is isolated from this plant for the first time.

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Available abstract

Objective To explore the chemical constituents of Isodon macrophyllus.Methods Compounds were separated and purified by silica gel column chromatography and their structures were elucidated on the basis of spectral data and chemical evidences. Results Six compounds were obtained from EtOAc extract of leaves of Isodon macrophyllus and identified as Epinodosin (1),Isodonoiol (2),Lasiodonin (3), Oridonin (4),Adenolin E (5),Lasiodin (6).Conclusion All of them are known.Compound 5 is isolated from this plant for the first time.

Key concepts: Chemical constituents, Chemistry, Column chromatography, Silica gel, Traditional medicine, Chromatography, Medicine

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