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Triterpenoid constituents of Isodon macrophyllus

Qiu Pei-yong

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Abstract

Objective To study the triterpenoid constituents of isodon macrophyllus.Methods Compounds were separated and purified by silica gel column chromatography and their structures were elucidated on the basis of spectral data and chemical evidences.Results Four compounds were obtained from ethyl acetate extract of leaves of Isodon macrophyllus and identified as ursolic acid(1),2α,3α-dihydroxy-urs-12-en-28-oic acid(2),2α,3α,24-trihydroxy-urs-12-en-28-oic acid(3),2α,3β,23-trihydroxy-urs-12-en-28-oic acid(4).Conclusion Four compounds are triterpenoid,and they are isolated from this plant for the first time.

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What this paper is about

Objective To study the triterpenoid constituents of isodon macrophyllus.Methods Compounds were separated and purified by silica gel column chromatography and their structures were elucidated on the basis of spectral data and chemical evidences.Results Four compounds were obtained from ethyl acetate extract of leaves of Isodon macrophyllus and identified as ursolic acid(1),2α,3α-dihydroxy-urs-12-en-28-oic acid(2),2α,3α,24-trihydroxy-urs-12-en-28-oic acid(3),2α,3β,23-trihydroxy-urs-12-en-28-oic acid(4).Conclusion Four compounds are triterpenoid,and they are isolated from this plant for the first time.

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Available abstract

Objective To study the triterpenoid constituents of isodon macrophyllus.Methods Compounds were separated and purified by silica gel column chromatography and their structures were elucidated on the basis of spectral data and chemical evidences.Results Four compounds were obtained from ethyl acetate extract of leaves of Isodon macrophyllus and identified as ursolic acid(1),2α,3α-dihydroxy-urs-12-en-28-oic acid(2),2α,3α,24-trihydroxy-urs-12-en-28-oic acid(3),2α,3β,23-trihydroxy-urs-12-en-28-oic acid(4).Conclusion Four compounds are triterpenoid,and they are isolated from this plant for the first time.

Key concepts: Ursolic acid, Chemistry, Silica gel, Terpene, Triterpenoid, Ethyl acetate, Column chromatography, Chemical constituents

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