Clinical Research on Correlation Factors of Concurrent Fungal Infections in Old Patients with Pulmonary Diseases:49 Case Reports

Objective:To study the susceptible factors,clinical features and treatments of nosocomial pulmonary fungal infection in the ward of respiratory department.Methods:The chart files of 49 patients with nosocomial pulmonary fungal infection admitted from January 2002 to June 2008 in the ward of Respiratory Department were reviewed.Results:The incidence rate of nosocomial pulmonary fungal infection was 3.78%.COPD(49.8%)was the main predisposing disease,and candidiasis(62.6%) was the most common pathogen.The main susceptible factors associated with nosocomial pulmonary fungal infection are long-term use of broad-spectrum antibiotics(96.2%),hypoalbuminemia(58.3%),long-term use of adrenocortical steroid(33.2%),and diabetes mellitus.There is no specific clinical feature.Fluconazole(91.4%)is more efficient in the treatment.Conclusion:Nosocomial pulmonary fungis are important pathogenin the secondary infection in respiratory disease.The most common pathogen is candida albicans.Combined therapy as well as treating fungus infection are important measures to increase the cure rate of nosocomial pulmonary fungal infection.