Comparison of effects of dinoprostone and oxytocin on cervical ripening and induced abortion of full term pregnancy

Objective:To compare the effects of dinoprostone and oxytocin on cervical ripening and induced abortion of full term pregnancy.Methods:60 full-term pregnant women(head position,single pregnancy,without contraindication of vaginal delivery and prostaglandin application) were divided into observation group(30 cases) and control group(30 cases);dinoprostone was put into the posterior fornix of pregnant women in observation group for one pellet,and small dose oxytocin was pumped into vein of pregnant women in control group;the Bishop scores,success rates of induced abortion,rates of cesarean section and neonatal outcomes in the two groups before and after treatment were compared.Results:At 6 and 12 hours after treatment,the Bishop scores in observation group were(5.41±0.86) and(7.82±1.05),respectively,which were significantly higher than those in control group,the effect of cervical ripening in observation group was superior to that in control group;the success rates of induced abortion in observation group and control group were 93.3% and 53.3%,respectively,there was significant difference between the two groups;the rates of cesarean section in observation group and control group were 23.3% and 46.7%,respectively,there was significant difference between the two groups;there was no significant difference in neonatal outcomes between the two groups.Conclusion:Dinoprostone is a safe and effective drug for cervical ripening and induced abortion,which can reduce the rate of cesarean section.