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2007•Journal of Hunan Normal UniversityRequires access

Value of cTnT in the Diagnosis of Acute Myocardial Infarction

Zhengbin Zhu

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Abstract

Objective To compare the value cardiac troponin(cTnT),creatine kinase(CK) and MB isoenzyme of creatine kinase(CK-MB)in detection of acute myocardial infarction(AMI).Methods Cardiac troponin T of 36 patients with AMI,45 patients with uncertain minor myocardial damage(MMD) angina and 38 healthy persons were detected by ELISA,compared with CK and and CK-MB.Results There was no significant differences in cTnT,CK and CK-MB of AMI patients(abnormal rate between 97% and 100%),but for angina patients,abnormal rate of cTnT(35.5%) was much higher than that of CK(8.9%) and CK-MB(13.3%);and cTnT of angina patients was much higher than that of healthy persons(P0.01).Conclusion cTnT is of much sensitivity and specificity than CK and CK-MB for the detection of AMI.

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Objective To compare the value cardiac troponin(cTnT),creatine kinase(CK) and MB isoenzyme of creatine kinase(CK-MB)in detection of acute myocardial infarction(AMI).Methods Cardiac troponin T of 36 patients with AMI,45 patients with uncertain minor myocardial damage(MMD) angina and 38 healthy persons were detected by ELISA,compared with CK and and CK-MB.Results There was no significant differences in cTnT,CK and CK-MB of AMI patients(abnormal rate between 97% and 100%),but for angina patients,abnormal rate of cTnT(35.5%) was much higher than that of CK(8.9%) and CK-MB(13.3%);and cTnT of angina patients was much higher than that of healthy persons(P0.01).Conclusion cTnT is of much sensitivity and specificity than CK and CK-MB for the detection of AMI.

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Available abstract

Objective To compare the value cardiac troponin(cTnT),creatine kinase(CK) and MB isoenzyme of creatine kinase(CK-MB)in detection of acute myocardial infarction(AMI).Methods Cardiac troponin T of 36 patients with AMI,45 patients with uncertain minor myocardial damage(MMD) angina and 38 healthy persons were detected by ELISA,compared with CK and and CK-MB.Results There was no significant differences in cTnT,CK and CK-MB of AMI patients(abnormal rate between 97% and 100%),but for angina patients,abnormal rate of cTnT(35.5%) was much higher than that of CK(8.9%) and CK-MB(13.3%);and cTnT of angina patients was much higher than that of healthy persons(P0.01).Conclusion cTnT is of much sensitivity and specificity than CK and CK-MB for the detection of AMI.

Key concepts: Troponin complex, Medicine, Myocardial infarction, Internal medicine, Cardiology, Creatine kinase, Angina, Troponin

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