Risk Factors for Dementia after Cerebral Infarction

Objective To study the incidence of and risk factors for dementia after the cerebral infarction. Methods Two hundred cases of cerebral infarction were selected. At admission, the medical history was asked in detail, blood biochemical test was carried out, the damage of nerve system MMSE was evaluated three months after cerebral infarction and the intelligent assessment was performed. Results Among the 200 cases of cerebral infarction, dementia occurred in 65 cases (32.5 %). Senility, low educational level, no occupation, insufficient family support, stroke history and bad life ability were the factors for the occurrence of dementia following the cerebral infarction. After cerebral infarction, creatine, blood glucose, fibrinogen and triglyceride in dementia group were significantly higher than in non-dementia group (P0.05, P0.01), but there was no significant difference in the lipoprotein between two groups (P0.05). The incidence of cerebral infarction in left sphere was lower than in right sphere. Multiple cerebral infarction and large size and severe damage of nerve system MMSE were related with the occurrence of dementia following the cerebral infarction (P0.01). Conclusion Dementia often occurs after cerebral infarction. It is related with following factors: age, educational level, occupation, insufficient family support, stroke history, the site and size of cerebral infarction, the focus number, the damage of nerve system, blood glucose, fibrinogen, lipoprotein, triglyceride and creatine etc.