Observation about curative effect of lactobacillus and clotrimazole on vulvovaginal candidiasis in pregnancy

OBJECTIVE To investigate the curative effect of lactobacillus combined with clotrimazole on vulvovaginal candidiasis in pregnancy. METHODS 112 pregnant patients with vulvovaginal candidiasis were randomly divided into two groups from the outpatient department during January 2010 to December 2010. The 56 patients in treatment group were treated with lactobacillus and clotrimazole, and the 56 patients in the control group were treated with clotrimazole alone. Clinical effect, mincroscopy examination of vaginal discharge and recurrence of vulvovaginal candidiasis in pregnacy were compared at the 10th, 30th and 60th after treatment. RESULTS There was no significant difference in the cure rate between the two groups 10th after the treatment (P0. 05) , while there was a significantly difference in relapse rate between the two groups 30th and 60th after treatment. CONCLUSION The lactobacillus and clotrimazole have long- lasting curative effect and low relapse rate in the treatment of vulvovaginal candidiasis in pregnancy.