Study on Speciation Analysis of Trace Elements in Morinda officinalis

Objective To aralyze the speciation of trace elements in Morinda officinalis.Methods 13 trace elements in the drug material as well as the respective dissolved rates in the decoction were measured by ICP-MS.Sub-speciation of 9 trace elements in the decoction was also analyzed,including the soluble state,suspended state,both the n-C8H17OH-soluble and water-soluble states in the n-C8H17OH-water extraction system.Results Different kinds of trace elements were found in the Morinda officinalis in which the richest is,in turn,Mn,Fe,Zn,Pb and Cu.The size of the dissolved rate did not depend on the content of trace element in the drug material.About 9 trace elements in the decoction,Se,Mn and Co existed mainly in the soluble speciation while the rest 6 ones mainly in the suspended speciation.It was found that the content of Se,Fe,Pb and Cu,Cd under the pH of intestinal juice was relatively higher while the others relatively lower in the n-C8H17OH-soluble speciation.It proved that Kow value of each trace element is influenced by different pH Values.The ICP-MS analytical methord is highly linear,accurate as well as dependable.Conclusion Different kinds of life elements have been found in the Morinda officinalis.The size of the dissolved rate depend on the elemental speciation in the drug material.The distribution of the soluble state and suspended state,is probably related to the elemental speciation and the characteristic of decoction.The distribution of the n-C8H17OH-soluble and water-soluble states must be contacted to the components and the stability of with which the elements combine.