Control of Blood Pressure and Heart Rate of Hypertension with Acute Coronary Syndrome Treated by Diltiazem Combined with Esmolol

Objective To evaluate the effects of diltiazem combined with esmolol on blood pressure(BP) and heart rate(HR) in patients with hypertension and acute coronary syndrome(ACS).Method 48 patients with hypertension and acute coronary syndrome were selected and divided into two groups randomly as observation group and control group.Each group contains 24 patients.The observation group received diltiazem combined with esmolol treatment while the control group received esmolol treatment.The BP,HR,ECG,and syndrome remission of all patients were observed before and after treatment.Results There was a significant difference(P0.05) in SBP/DBP,HR and ECG after the treatment in 4 hours between two groups.The observation group has better clinical effect than the control group in the respects of BP,HR,ECG,and syndrome remission.Conclusion With no more adverse reactions,diltiazem combined with esmolol is more effective in patients with acute coronary syndrome.