Analysis the clinical efficacy of Bi level positive airway pressure ventilation in treating chronic obstructive pulmonary diseases with typell respiratory failure

Objective To investigate the effect of Bi level positive airway pressure ventilation(BiPAP) on acute exacerbation of chronic obstructive pulmonary disease(AECOPD) patients with type II respiratory failure.Methods 120 patients with AECOPD complicated with type II respiratory failure were divided into 2 groups,60 cases in each group.TWO groups were given conventional treatment,the treatment group was given BiPAP,the control group was given continuous nasal catheter inhalation of low flow oxygen,before and after treatment,heart rate,respiratory frequency,pH72 h value of pressure,carbon dioxide(PaCO_2),partial pressure of oxygen(PaO_2),oxygen saturation(SaO_2),and the average hospitalization time were observed in the 2 groups.Results The heart rate,respiratory frequency,PaCO_2 of the 2 groups were significantly reduced(P 0.01),pH value,PaO_2,SaO_2 were significantly increased than before treatment(P 0.01);and the treatment group patients;heart rate,respiratory rate,PaCO_2' s decline was significantly greater than the control group,PaO_2,SaO_2 markedly increased than that of the control group(P 0.01 or P 0.05);no significant difference of pH values were found in the 2 groups after treatment(P 0.05).The average duration time of the control group was(10.81 ±3.26) d,longer than the treatment group's(9.41 ±2.73) d,the difference was statistically significant(P 0.05).Conclusion It suggested that BiPAP ventilation on patients with AECOPD complicated with hypoxemia,hypercapnia and type II respiratory failure has obvious curative effect,it can improve oxygenation,and shorten the time of hospitalization,worthy of promotion.