Effect of bilevel positive airway pressure ventilation on patients with chronic pulmonary heart disease combined with type II respiratory failure

Objective To investigate the effect of bilevel positive airway pressure(BiPAP) ventilation on chronic pulmonary heart disease combined with typeⅡrespiratory failure.Methods Eighty patients with pulmonary heart disease combined with typeⅡrespiratory failure were divided into two groups,forty cases in each group.The patients in control group were given with conventional general treatment only while the patients in observation group were given with BiPAP ventilation besides conventional treatment.Three hours before treatment and seventy two hours after treatment,arterial oxygen saturation(SaO2),power of hydrogen(pH),partial pressure of oxygen in artery(PaO2),partial pressure of carbon dioxide in artery(PaCO2),heart rate(HR) and respiratory rate(RR) were compared between two groups.Results Before treatment,there was no significant difference in SaO2,pH,PaO2,PaCO2,HR and BR between two groups(P0.05).Compared with before treatment,SaO2,PaO2 and pH were higher(P0.05),but HR,BR and PaCO2 were lower(P0.05,P0.01) after treatment in two groups.After treatment,SaO2,PaO2 and pH in observation group were higher than those in control group(P0.05),but PaCO2 was lower(P0.05).There was no significant difference in HR and BR between two groups after treatment(P0.05).There was no severe adverse effect in two groups.Conclusion Using BiPAP noninvasive ventilation to treat patients with chronic pulmonary heart disease combined with typeⅡrespiratory failure can improve blood gas analysis and clinical symptoms.