Effect of Telmisartan on left ventricular hypertrophy and earlier period renal dysfunction in patients with essential hypertension

AIM: To evaluate the effect of Telmisartan on target organ damage in patients with mild to moderate hypertension. METHODS: 60 patients with mild to moderate hypertension complicated with left ventricular hypertrophy were treated with Telmisartan for 26 weeks. The IVST,LVPWT,A/E,LVMI were checked by echocardiography and the concentrations of serum β 2-MG and urine β 2-MG were determined before and after treatment. RESULTS: Both SBP and DBP decreased after the treatment of Telmisartan ,the effective rates were 72%, LVMI,A/E,serum β 2-MG and urine β 2-MG significantly decreased after Telmisartan treatment. CONCLUSION: Telmisartan was effective not only in treating of hypertension but also in preventing heart and kidney from dysfunction.