Association of Elevated B-Type Natriuretic Peptide Levels With Angiographic Findings Among Patients With Acute Myocardial Infarction

Objective: We hypothesized that elevated B-type natriuretic peptide(BNP) levels would be associated with a greater severity of angiographic disease and a greater extent of myocardium at risk in patients with acute myocardial infarction(AMI).Methods: In this retrospective study,consecutive 149 patients with STEMI and 63 with NSTEMI were included.These patients were separated into STEMI group and NSTEMI group.Results: The proportion of previous MI(12.7%) and PTCA(15.9%) and left ventricular ejection fraction in NSTEMI group was higher than STEMI group.Circumflex artery as the culprit vessel was more often in NSTEMI group(38.1%) than in STEMI group(12.1%,P0.0001).There was no correlation between BNP level and the number of narrowed coronary artery in patients with AMI.In STEMI group,BNP level was higher when LAD as culprit vessel than circumflex artery or right coronary artery.In NSTEMI group,there was no correlation between BNP levels and culprit lesion location.Conclusions: BNP levels were higher in patients with STEMI with anterior wall location.BNP had no predictive value on culprit lesion location in patients with NSTEMI.