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Artificial Liver Support System in Severe Hepatitis: Clinical Analysis of 24 Cases

Sun Xiu-guang

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Abstract

Objective To study the therapeutic effect of artificial liver support system(ALSS) in severe hepatitis. Methods Twenty-four patients with severe hepatitis were treated with 40 case-times of plasma exchang and hemodialysis by WLXGX-888 ALSS. Liver function, prealbumin(PA), prothrombin activity(PTa), NH 3, dielectric were tested before and after therapeuty. Results Liver functions were obviously ameliorated after the treatment with ALSS, total bilirubin(TBIL), blood NH 3 and dielectric, total protein were obviously decreasing(P0.001). Albumin was decreasing, P0.05. PA was obviously increasing, P 0.001. The general effective rate of subacute, chronic severe hepatitis were 71.43 % and 44.44 %. None was dead in late period. Conclusion It is safe and effective on patients with ALSS and living rate of patients with severe hepatitis is obviously increasing.

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What this paper is about

Objective To study the therapeutic effect of artificial liver support system(ALSS) in severe hepatitis. Methods Twenty-four patients with severe hepatitis were treated with 40 case-times of plasma exchang and hemodialysis by WLXGX-888 ALSS. Liver function, prealbumin(PA), prothrombin activity(PTa), NH 3, dielectric were tested before and after therapeuty. Results Liver functions were obviously ameliorated after the treatment with ALSS, total bilirubin(TBIL), blood NH 3 and dielectric, total protein were obviously decreasing(P0.001). Albumin was decreasing, P0.05. PA was obviously increasing, P 0.001. The general effective rate of subacute, chronic severe hepatitis were 71.43 % and 44.44 %. None was dead in late period. Conclusion It is safe and effective on patients with ALSS and living rate of patients with severe hepatitis is obviously increasing.

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Available abstract

Objective To study the therapeutic effect of artificial liver support system(ALSS) in severe hepatitis. Methods Twenty-four patients with severe hepatitis were treated with 40 case-times of plasma exchang and hemodialysis by WLXGX-888 ALSS. Liver function, prealbumin(PA), prothrombin activity(PTa), NH 3, dielectric were tested before and after therapeuty. Results Liver functions were obviously ameliorated after the treatment with ALSS, total bilirubin(TBIL), blood NH 3 and dielectric, total protein were obviously decreasing(P0.001). Albumin was decreasing, P0.05. PA was obviously increasing, P 0.001. The general effective rate of subacute, chronic severe hepatitis were 71.43 % and 44.44 %. None was dead in late period. Conclusion It is safe and effective on patients with ALSS and living rate of patients with severe hepatitis is obviously increasing.

Key concepts: Medicine, Artificial liver, Hepatitis a virus, Transthyretin, Internal medicine, Liver function, Albumin, Gastroenterology

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