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2006•Chinese Journal of Dialysis and Artificial OrgansRequires access

Study on the Treatment of Severe Hepatitis with Artificial Liver Support System(ALSS)

Yong‐Ping Chen

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Abstract

Objective To study the curative effect as well as the mechanism of artificial liver support system in the treatment of severe hepatitis.Methods 62 patients suffering from severe hepatitis were treated with ALSS.The concentration of ammonia,TNF-α,IL-10 and liver function were detected before and after therapy.Results It showed that liver function was significantly improved after ALSS therapy.There were significant decreases in the concentration of ammonia,TNF-α,and the concentration of IL-10 was increased.Conclusion The ALSS treatment will effectively remove the pathological compositions,including total bilirubin,ammonia,TNF-α,and it is available to improve the survival rate.

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What this paper is about

Objective To study the curative effect as well as the mechanism of artificial liver support system in the treatment of severe hepatitis.Methods 62 patients suffering from severe hepatitis were treated with ALSS.The concentration of ammonia,TNF-α,IL-10 and liver function were detected before and after therapy.Results It showed that liver function was significantly improved after ALSS therapy.There were significant decreases in the concentration of ammonia,TNF-α,and the concentration of IL-10 was increased.Conclusion The ALSS treatment will effectively remove the pathological compositions,including total bilirubin,ammonia,TNF-α,and it is available to improve the survival rate.

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Available abstract

Objective To study the curative effect as well as the mechanism of artificial liver support system in the treatment of severe hepatitis.Methods 62 patients suffering from severe hepatitis were treated with ALSS.The concentration of ammonia,TNF-α,IL-10 and liver function were detected before and after therapy.Results It showed that liver function was significantly improved after ALSS therapy.There were significant decreases in the concentration of ammonia,TNF-α,and the concentration of IL-10 was increased.Conclusion The ALSS treatment will effectively remove the pathological compositions,including total bilirubin,ammonia,TNF-α,and it is available to improve the survival rate.

Key concepts: Artificial liver, Hepatitis a virus, Gastroenterology, Bilirubin, Liver function, Medicine, Internal medicine, Ammonia

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