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2005•Unpublished venueRequires access

New antipsychotics in accessory treatment of mania episode

MA Tang-y

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Abstract

Objective:To compare the efficacy and side effects o f risperidone or olanzapine combined with lithium respectively in the treatment of mania episode in bipolar disorder. Method:66 manic patients were randomly assigned to be treated by risperidone or olanzapine combined with lithium respectively for 6 weeks. All the patients were evaluated by Bech-Rafae lsen mania rating scale (BRMS),GAS,CGI-SI,TESS and laboratory test. Re sults:In both groups,total score of BRMS was significantly reduced from baseline, and there were no significant differences between two groups.Few side effects were observed. Conclusion:Risperidone or olanzapine com bined with lithinm therapy is safe and efficacious in the treatment of mania.

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Objective:To compare the efficacy and side effects o f risperidone or olanzapine combined with lithium respectively in the treatment of mania episode in bipolar disorder. Method:66 manic patients were randomly assigned to be treated by risperidone or olanzapine combined with lithium respectively for 6 weeks. All the patients were evaluated by Bech-Rafae lsen mania rating scale (BRMS),GAS,CGI-SI,TESS and laboratory test. Re sults:In both groups,total score of BRMS was significantly reduced from baseline, and there were no significant differences between two groups.Few side effects were observed. Conclusion:Risperidone or olanzapine com bined with lithinm therapy is safe and efficacious in the treatment of mania.

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Available abstract

Objective:To compare the efficacy and side effects o f risperidone or olanzapine combined with lithium respectively in the treatment of mania episode in bipolar disorder. Method:66 manic patients were randomly assigned to be treated by risperidone or olanzapine combined with lithium respectively for 6 weeks. All the patients were evaluated by Bech-Rafae lsen mania rating scale (BRMS),GAS,CGI-SI,TESS and laboratory test. Re sults:In both groups,total score of BRMS was significantly reduced from baseline, and there were no significant differences between two groups.Few side effects were observed. Conclusion:Risperidone or olanzapine com bined with lithinm therapy is safe and efficacious in the treatment of mania.

Key concepts: Mania, Olanzapine, Risperidone, Lithium (medication), Young Mania Rating Scale, Bipolar disorder, Psychology, Psychiatry

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