Valsartan treatment of chrouic congestive heart failure chinical value

Objective This study was to investigate the clinical value of Valsartan on congestive heart failure(CHF) Methods 80 cases of congestive heart failure in patients on the basis of conventional therapy(digitalis、diuretics、 vasodilators) were randomly divided into enalapril group(n=40),served enolapril 2.5~20 mg/d,valsartan group(n=40),served valsartan 40~160 mg/d.for a total of six months.The changes in the heart function and the distance for 6 minutes walking test cardiac echocardiogrphic parameters were assessed before and after treatment.Results After 6 months therapy,cardiac function(NYHA classification)、distance for 6 minutes walking test、left ventricular ejection fraction(EF)、LV end-distolic volume(EDV)、LV end-systolic volume(ESV) were improved significantly in both groups(P0.01),but after treatment between the two groups above indicators there was no significant difference(P0.05).The incidence of side effects between two groups was significant difference(P0.05).Conclusion Valsartan is as effective as enalapril in the treatment of the patients with CHF and it is well tolerated.