Preparation and Quality Standards of Effective Parts of Sacandra Glabra Capsule

Objective: To optimize the preparation and set up the quality standard of Sarcandra glabra capsule. Methods: Investigate liquidity,hygroscopicity and bulk density of Sarcandrae extract powder. TLC,UV and HPLC were used to identify and determine the contents of total flavonoids and Isofraxidin. Results: The angle of Sarcandrae extract powder was 26. 26°; moisture percentage was 9. 68% after 72h; bulk density was 0. 73g / ml. TLC spots were clear; the average moisture content of capsule was 3. 27%; load difference was 1. 32%; the dissolution of total flavonoids and isofraxidin were 82. 14% and 99. 92% after 40 min; the linear range of rutin was 0. 02 ~ 0. 07mg / ml( r = 0. 9997) with an average recovery of 101. 19%. The linear range of isofraxidin was 0. 0001 ~ 0. 0005μg( r = 0. 9998) with an average recovery of 100. 64%. The contents of both effective parts were not less than 160mg and 4mg. Conclusion: The preparation process is reasonable and easy to operate,and it can be used for the quality control of Sarcandra glabra capsule.