2006•Unpublished venueRequires access

Effects of experimental varicocele on the apoptosis of spermatogenic cell in adolescent rats

Hong Han-y

Abstract

Objective To study the effects of experimental varicocele on the apoptosis of spermatogenic cell in adolescent rats.Methods Experimental varicocele models were created by partial ligation of left renal vein in Sprague-Dawley(SD) male rats.The apoptosis of spermatogenic cells was detected by in situ terminal deoxylnucleotidyl transferase mediated-dUTP nick end labeling(TUNEL) technique.Results The incidence of apoptosis was increased significantly in experimental group than that in control group(P0.001),and the apoptosis number of spermatogenic cells of bilateral testes was increased.Conclusion The apoptosis of spermatogenic cells of bilateral testes caused by left varicocele may be one of the mechanisms of male sterility caused by varicocele.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Varicocele, TUNEL assay, Apoptosis, Left renal vein, Ligation, Andrology, Internal medicine, Epididymis