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2014•Guide of China MedicineRequires access

The Clinical Value of Adenosine Deaminase in the Diagnosis of Tuberculous Pleurisy

Jiang Xiu-hu

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Abstract

Objective To study the relationship between theADA rising in pleural effusion and tuberculous pleuritis, so as to prefer early chemotherapy. Methods 336 cases with pleural effusion were tested with PPD and ADA activity was determined by enzyme kinetic analytical method respectively at the same time. Hydrothorax ADA for diagnosis in patients with tubeiculous pleurisy. Results Statistical analysis suggest significant differences of sensitivity and specificity between ADA and PPD(P0.05). the former sensitivity was higher(94.04 %) and specificity(88.8 %) than that of the later(90.18 %),(82.1 %). Conclusion ADA test has active value in early for tuberculous pleural effusion and its chemotherapy.

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What this paper is about

Objective To study the relationship between theADA rising in pleural effusion and tuberculous pleuritis, so as to prefer early chemotherapy. Methods 336 cases with pleural effusion were tested with PPD and ADA activity was determined by enzyme kinetic analytical method respectively at the same time. Hydrothorax ADA for diagnosis in patients with tubeiculous pleurisy. Results Statistical analysis suggest significant differences of sensitivity and specificity between ADA and PPD(P0.05). the former sensitivity was higher(94.04 %) and specificity(88.8 %) than that of the later(90.18 %),(82.1 %). Conclusion ADA test has active value in early for tuberculous pleural effusion and its chemotherapy.

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Available abstract

Objective To study the relationship between theADA rising in pleural effusion and tuberculous pleuritis, so as to prefer early chemotherapy. Methods 336 cases with pleural effusion were tested with PPD and ADA activity was determined by enzyme kinetic analytical method respectively at the same time. Hydrothorax ADA for diagnosis in patients with tubeiculous pleurisy. Results Statistical analysis suggest significant differences of sensitivity and specificity between ADA and PPD(P0.05). the former sensitivity was higher(94.04 %) and specificity(88.8 %) than that of the later(90.18 %),(82.1 %). Conclusion ADA test has active value in early for tuberculous pleural effusion and its chemotherapy.

Key concepts: Medicine, Adenosine deaminase, Hydrothorax, Pleural effusion, Internal medicine, Pleurisy, Chemotherapy, Gastroenterology

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