2007Journal of Hebei North UniversityRequires access

Test for Adenosine Deaminase in Pleural Effusion for Diagnosing Tuberculous Pleuritis

Zhao Jian-qing

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Abstract

Objective: To study the relationship between the ADA rising in pleural effusion and tuberculous pleuritis,so as to prefer early chemotherapy.Methods: 436 cases with pleural effusion were tested with PPD and ADA activity was determined by enzyme kinetic analytical method respectively at the same time.All the patients had never been treated with chemotherapy for tuberculosis.Results: Statistical analysis suggest significant differences of sensitivity and specificity between ADA and PPD(P0.05),the former sensitivity was higher(96.1%) than that of the later(90.2%).Conclusion: ADA test has active value in early diagnosis for tuberculous pleural effusion and its chemotherapy.

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What this paper is about

Objective: To study the relationship between the ADA rising in pleural effusion and tuberculous pleuritis,so as to prefer early chemotherapy.Methods: 436 cases with pleural effusion were tested with PPD and ADA activity was determined by enzyme kinetic analytical method respectively at the same time.All the patients had never been treated with chemotherapy for tuberculosis.Results: Statistical analysis suggest significant differences of sensitivity and specificity between ADA and PPD(P0.05),the former sensitivity was higher(96.1%) than that of the later(90.2%).Conclusion: ADA test has active value in early diagnosis for tuberculous pleural effusion and its chemotherapy.

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Available abstract

Objective: To study the relationship between the ADA rising in pleural effusion and tuberculous pleuritis,so as to prefer early chemotherapy.Methods: 436 cases with pleural effusion were tested with PPD and ADA activity was determined by enzyme kinetic analytical method respectively at the same time.All the patients had never been treated with chemotherapy for tuberculosis.Results: Statistical analysis suggest significant differences of sensitivity and specificity between ADA and PPD(P0.05),the former sensitivity was higher(96.1%) than that of the later(90.2%).Conclusion: ADA test has active value in early diagnosis for tuberculous pleural effusion and its chemotherapy.

Key concepts: Adenosine deaminase, Medicine, Pleural effusion, Chemotherapy, Tuberculosis, Internal medicine, Gastroenterology, Pathology

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