2007•Journal of Hebei North UniversityRequires access

The Clinical Significance of VEGF Expression in Benign and Malignant Breast Tumour

BO Ai-hua

Abstract

Objective:To investigate the clinical significance of VEGF expression in human breast cancer.Methods:For 47 cases with breast tumor and 95 cases with breast cancer,VEGF were examined by SABC immunohistochemical methods.Results:The positive rate of VEGF was 25.53%(12/47) in the breast adenoma and the positive rate of VEGF was 54.75%(52/95) in breast cancer.The positive rates of VEGF in invasive breast cancer and lymphmetastases group were significantly higher than that of non-invasive group and non-lymphmetastases group(P0.05).Conclusion:The overexperssion of VEGF may be predict poor prognosis and VEGF examined is helpful for chemotherapy plan of breast cancer.

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Key concepts: Breast cancer, Medicine, VEGF receptors, Immunohistochemistry, Oncology, Internal medicine, Clinical significance, Vascular endothelial growth factor