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2010•China Practical MedicineRequires access

Efficacy of patient-controlled analgesia with flurbiprofen axetil and butorphanol/morphine in patients with advanced cancer

Yang Yong-m

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Abstract

Objective To compare the analgesic effect of flurbiprofen axetil and butorphanol/morphine during patient-controlled intravenous analgesia(PCIA)in patients with advanced cancer.Methods Totally 40 patients with Ⅱ ~ Ⅲ-class advanced cancer were randomly divided into two PCIA groups according to different analgesic drugs with 20 cases in each group:flurbiprofen axetil + butorphanol group(B group),flurbiprofen axetil + morphine group(M group).The Analgesia efficiency,sedation efficiency,life sign and side effect were observed for 48 hours(6 h,12 h,24 h,4 8 h).Results No statistical difference in the analgesic effect was found between the two groups(P0.05).Patients of B group had fewer incidences of adverse events than those of M group.Conclusion Patient-controlled intravenous analgesia with flurbiprofen axetil combined with butorphanol has satisfactory analgesic effect and fewer side effects in patients with advanced cancer.

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What this paper is about

Objective To compare the analgesic effect of flurbiprofen axetil and butorphanol/morphine during patient-controlled intravenous analgesia(PCIA)in patients with advanced cancer.Methods Totally 40 patients with Ⅱ ~ Ⅲ-class advanced cancer were randomly divided into two PCIA groups according to different analgesic drugs with 20 cases in each group:flurbiprofen axetil + butorphanol group(B group),flurbiprofen axetil + morphine group(M group).The Analgesia efficiency,sedation efficiency,life sign and side effect were observed for 48 hours(6 h,12 h,24 h,4 8 h).Results No statistical difference in the analgesic effect was found between the two groups(P0.05).Patients of B group had fewer incidences of adverse events than those of M group.Conclusion Patient-controlled intravenous analgesia with flurbiprofen axetil combined with butorphanol has satisfactory analgesic effect and fewer side effects in patients with advanced cancer.

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Available abstract

Objective To compare the analgesic effect of flurbiprofen axetil and butorphanol/morphine during patient-controlled intravenous analgesia(PCIA)in patients with advanced cancer.Methods Totally 40 patients with Ⅱ ~ Ⅲ-class advanced cancer were randomly divided into two PCIA groups according to different analgesic drugs with 20 cases in each group:flurbiprofen axetil + butorphanol group(B group),flurbiprofen axetil + morphine group(M group).The Analgesia efficiency,sedation efficiency,life sign and side effect were observed for 48 hours(6 h,12 h,24 h,4 8 h).Results No statistical difference in the analgesic effect was found between the two groups(P0.05).Patients of B group had fewer incidences of adverse events than those of M group.Conclusion Patient-controlled intravenous analgesia with flurbiprofen axetil combined with butorphanol has satisfactory analgesic effect and fewer side effects in patients with advanced cancer.

Key concepts: Butorphanol, Medicine, Analgesic, Morphine, Sedation, Anesthesia, Flurbiprofen, Adverse effect

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Efficacy of patient-controlled analgesia with flurbiprofen axetil and butorphanol/morphine in patients with advanced cancer — Research Paper | ScholarLens