The impact of non-invasive positive pressure ventilation in acute exacerbation of elderly patients with chronic obstructive pulmonary disease

Objective:To explore the non-invasive positive pressure ventilation(NIPPV) in acute exacerbation of elderly patients with chronic obstructive pulmonary disease(AECOPD) with respiratory failure.Methods: A retrospective analysis of 60 cases admitted in December 2008-2010 December elderly AECOPD complicated by respiratory failure in patients with clinical data.According to the different treatment methods,divided into the face(nose) mask bi-level positive pressure ventilation(BiPAP) treatment group(26 cases) and the conventional treatment group(34 cases).Were compared between the two groups,arterial partial pressure of oxygen(PaO2),partial pressure of carbon dioxide in artery(PaCO2),pH value,intubation rate,mortality.Results: Compared with the conventional treatment group,BiPAP treatment group intubation rate and low mortality.Compared with before treatment,treatment after 1~2 hours,72 hours and prior to discharge of BiPAP treatment group,PaO2,pH values increased.PaCO2 was lower,the difference was statistically significant.Conclusion: NIPPV can ease breathing machine fatigue,reasonable application of BiPAP therapy can significantly improve,PaO2,PaCO2,pH value and other physiologic parameters,reducing the rate of endotracheal intubation and reduce mortality,the treatment of elderly AECOPD complicated by respiratory failure of some clinical significance.