2005•Biaoji mianyi fenxi yu linchuangRequires access
Combined Detection of AM, CYFRA21-1, NSE and CEA Levels in Pleural Effusion for Differentiation of Malignant from Tuberculous Pleural Effusion
Yu Hua, Zhu Wenru, Sun Shuhong, Shuhua Xu, Hui Yu
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Abstract
The levels of four tumor markers(AM, CYFRA21-1, NSE and CEA) pleural effusion in plearal effusion were determined by RIA in 52 patients with tuberculous pleural effusion and 74 patients with malignant pleural effusion.The results showed that the levels of the four tumor markers in malignant pleural effusion were significantly higher than those in tuberculous pleural effusion.Combined detection of the four tumor markers could improve the diagnostic sensitivity and the accuracy to 90.5% and 92.9%,respectively(P0.01).Detection of AM, CYFRA21-1, NSE and CEA levels in pleural effusion is very useful for the differentiation of malignant from tuberculous pleural effusion.Combined detection of the four markers may greatly improve the diagnostic accuracy.