Study on the Effect of PERICARPIUM ZANTHOXYLI Extracts on Proliferation and Apoptosis of SGC-7901 Cell
Pin-Ai Li
Abstract
Pin-Ai Li
Abstract
[Objective] To study the effect of PERICARPIUM ZANTHOXYLI extracts on proliferation and apoptosis of SGC-7901 cell.[Method] The SGC-7901 cell was cultured in vitro.The inhibitory effect of PERICARPIUM ZANTHOXYLI extracts was determined by MTT;cell morphology was observed under optical microscope and electron microscope;cell apoptosis was detected by flow cytometry.[Result] PERICARPIUM ZANTHOXYLI extracts showed significant inhibitory effect to SGC-7901 cell,and the inhibitory effect was increased with the increase of concentration and time.The cell changed greatly in apoptosis characteristics.[Conclusion] PERICARPIUM ZANTHOXYLI extracts had potential anti-tumor value.
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[Objective] To study the effect of PERICARPIUM ZANTHOXYLI extracts on proliferation and apoptosis of SGC-7901 cell.[Method] The SGC-7901 cell was cultured in vitro.The inhibitory effect of PERICARPIUM ZANTHOXYLI extracts was determined by MTT;cell morphology was observed under optical microscope and electron microscope;cell apoptosis was detected by flow cytometry.[Result] PERICARPIUM ZANTHOXYLI extracts showed significant inhibitory effect to SGC-7901 cell,and the inhibitory effect was increased with the increase of concentration and time.The cell changed greatly in apoptosis characteristics.[Conclusion] PERICARPIUM ZANTHOXYLI extracts had potential anti-tumor value.
Key concepts: Apoptosis, Flow cytometry, Cell, Cell growth, MTT assay, In vitro, Inhibitory postsynaptic potential, Cell biology