Clinical significance of the change of serum high-sensitive C-reactive protein in patients with cerebral infarction

Objective To investigate the change of serum high-sensitive C-reactive protein(hs-CRP)levels and its clinical significance in patients with cerebral infarction.Methods The levels of serum hs-CRP in 50 patients with cerebral infarction at different periods(observation group)and 30 healthy subjects(control group)were detected by ELISA.Results(1)The levels of serum hs-CRP in observation group were significantly higher than those of control group at the 1st,3rd,7th,21st day after stroke onset(P0.05).The levels of hs-CRP in observation group at the 1st,3rd,7th were significantly higher than that at the 21st day(P0.05).(2)The levels of hs-CRP in observation group were positively correlated with the volume of cerebral infarction and the degree of neurological function defect(P0.01).Conclusion The changes of levels of serum hs-CRP may contribute to the evaluation of size of focus and prognosis,and to the prediction and intervention for cerebral infarction.